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patient_id
string
age_at_baseline_years
float64
race_ethnicity
string
height_cm
float64
weight_kg
float64
bmi_kg_m2
float64
insurance_type
string
geographic_region
string
pcos_phenotype_rotterdam
string
hyperandrogenism_flag
int64
oligo_anovulation_flag
int64
polycystic_ovary_morphology_flag
int64
menstrual_pattern
string
menstrual_cycle_length_days
float64
menstrual_cycles_per_year
float64
hirsutism_flag
int64
ferriman_gallwey_score
float64
acne_flag
int64
alopecia_flag
int64
acanthosis_nigricans_flag
int64
diagnosis_age_years
float64
diagnosis_delay_years
float64
lh_mIU_ml
float64
fsh_mIU_ml
float64
lh_fsh_ratio
float64
gnrh_pulse_freq_per_hour
float64
estradiol_pg_ml
float64
estrone_pg_ml
float64
progesterone_ng_ml
float64
testosterone_total_ng_dl
float64
testosterone_free_pg_ml
float64
shbg_nmol_l
float64
dheas_ug_dl
float64
androstenedione_ng_dl
float64
17oh_progesterone_ng_dl
float64
dihydrotestosterone_pg_ml
float64
anti_mullerian_hormone_ng_ml
float64
inhibin_b_pg_ml
float64
prolactin_ng_ml
float64
tsh_mIU_l
float64
free_t4_ng_dl
float64
cortisol_am_ug_dl
float64
acth_pg_ml
float64
lh_trajectory_annual_json
string
testosterone_trajectory_annual_json
string
amh_trajectory_annual_json
string
testosterone_elevated_flag
int64
lh_fsh_ratio_elevated_flag
int64
amh_elevated_flag
int64
prolactin_elevated_flag
int64
hypothyroidism_flag
int64
fasting_glucose_mg_dl
float64
fasting_insulin_uIU_ml
float64
homa_ir
float64
homa_beta
float64
quicki_score
float64
ogtt_2hr_glucose_mg_dl
float64
ogtt_insulin_peak_uIU_ml
float64
hba1c_pct
float64
glycemic_category
string
insulin_resistance_flag
int64
t2dm_progression_flag
int64
adiponectin_ug_ml
float64
leptin_ng_ml
float64
ghrelin_pg_ml
float64
c_peptide_ng_ml
float64
visceral_adiposity_index
float64
waist_circumference_cm
float64
waist_hip_ratio
float64
total_cholesterol_mg_dl
float64
ldl_mg_dl
float64
hdl_mg_dl
float64
triglycerides_mg_dl
float64
non_hdl_cholesterol_mg_dl
float64
apob_mg_dl
float64
lp_a_nmol_l
float64
crp_mg_l
float64
il6_pg_ml
float64
tnf_alpha_pg_ml
float64
sbp_mmhg
float64
dbp_mmhg
float64
metabolic_syndrome_flag
int64
metabolic_syndrome_criteria_count
int64
nafld_flag
int64
sleep_apnea_flag
int64
homa_ir_trajectory_annual_json
string
antral_follicle_count_right
int64
antral_follicle_count_left
int64
antral_follicle_count_total
int64
ovarian_volume_right_ml
float64
ovarian_volume_left_ml
float64
ovarian_volume_total_ml
float64
follicle_size_dominant_mm
float64
stromal_to_ovarian_area_ratio
float64
stroma_echogenicity
string
endometrial_thickness_mm
float64
endometrial_pattern
string
endometrial_hyperplasia_flag
int64
endometrial_cancer_flag
int64
uterine_fibroids_flag
int64
ovarian_cyst_hemorrhagic_flag
int64
ultrasound_modality
string
afc_rotterdam_criterion_flag
int64
ovarian_volume_criterion_flag
int64
fertility_intent_flag
int64
infertility_duration_years
float64
ovulation_induction_type
string
letrozole_dose_mg
float64
letrozole_ovulation_rate_pct
float64
letrozole_livebirth_rate_pct
float64
clomiphene_ovulation_rate_pct
float64
clomiphene_livebirth_rate_pct
float64
iui_cycles_count
int64
iui_pregnancy_rate_per_cycle_pct
float64
ivf_cycles_count
int64
ivf_oocytes_retrieved
int64
ivf_fertilization_rate_pct
float64
ivf_blastocyst_rate_pct
float64
ivf_clinical_pregnancy_rate_pct
float64
ivf_livebirth_rate_per_cycle_pct
float64
frozen_embryo_transfer_flag
int64
cumulative_livebirth_probability_3yr
float64
pregnancy_loss_count
int64
pregnancy_loss_rate_pct
float64
ectopic_pregnancy_flag
int64
gestational_diabetes_flag
int64
preeclampsia_flag
int64
preterm_birth_flag
int64
neonatal_icu_flag
int64
ohss_risk_category
string
ohss_event_flag
int64
ohss_hospitalization_flag
int64
time_to_first_conception_months
float64
livebirth_flag
int64
treatment_flag
int64
treatment_type
string
ocp_progestin_type
string
ocp_duration_months
int64
ocp_testosterone_reduction_pct
float64
ocp_shbg_increase_pct
float64
metformin_dose_mg_day
int64
metformin_hba1c_reduction_pct
float64
metformin_ovulation_improvement_flag
int64
spironolactone_dose_mg_day
int64
spironolactone_fg_score_reduction_pct
float64
glp1_ra_flag
int64
glp1_bmi_reduction_pct
float64
glp1_homa_ir_reduction_pct
float64
inositol_supplement_flag
int64
laser_electrolysis_flag
int64
treatment_adherence_pct
float64
treatment_duration_months
int64
treatment_response_flag
int64
drug_switch_flag
int64
cardiovascular_risk_score_10yr_pct
float64
cvd_event_flag
int64
stroke_flag
int64
hypertension_onset_age_years
float64
carotid_imt_mm
float64
coronary_calcium_score_agatston
int64
endothelial_dysfunction_flag
int64
endometrial_cancer_lifetime_risk_pct
float64
ovarian_cancer_flag
int64
breast_cancer_flag
int64
depression_flag
int64
anxiety_flag
int64
eating_disorder_flag
int64
pcos_quality_of_life_pcosq
float64
sexual_dysfunction_flag
int64
body_image_distress_flag
int64
vitamin_d_25oh_ng_ml
float64
ferritin_ng_ml
float64
hemoglobin_g_dl
float64
alt_iu_l
float64
ast_iu_l
float64
egfr_ml_min_173m2
float64
uric_acid_mg_dl
float64
heart_rate_bpm
int64
ob_gyn_visits_per_year
int64
endocrinology_referral_flag
int64
reproductive_endocrinology_referral_flag
int64
dermatology_referral_flag
int64
mental_health_referral_flag
int64
dietitian_referral_flag
int64
ultrasound_count_total
int64
lab_panel_count_per_year
int64
total_fertility_treatment_cost_usd
float64
total_healthcare_cost_usd
float64
ivf_episode_cost_usd
float64
medication_annual_cost_usd
float64
PCOS-0000001
30.1
Hispanic
153.9
79
33.4
Medicaid
Urban
C
1
0
1
Regular
26.7
13
1
15.1
0
0
0
25.9
2.4
2.7
7.74
0.35
1.44
74.2
98.6
13.83
62.8
25
91.1
246
208.9
46
42.2
6.11
156.4
14.5
4.77
1.072
11.1
35.4
[2.53, 2.0, 2.0, 3.68, 3.82, 3.52, 2.0, 3.05, 2.88, 3.03, 4.01, 3.04, 3.72, 2.8, 3.14]
[65.29, 56.93, 61.48, 60.88, 60.2, 61.66, 68.74, 59.3, 66.63, 56.03, 61.42, 63.41, 65.11, 65.61, 65.93]
[6.04, 5.9, 6.05, 5.72, 5.38, 5.29, 5.21, 5.37, 5.18, 5.17, 4.83, 4.83, 4.8, 4.49, 4.53]
1
0
1
0
1
87.2
14.2
3.07
102.3
0.28
91.6
182.8
4.8
NGT
1
0
12.74
39.5
443
1.74
2.46
90.4
1.05
147.1
94
36.4
83.4
110.7
101.9
30
5.08
3.32
5.21
109
76
0
2
1
0
[3.23, 2.72, 3.15, 3.11, 2.95, 2.78, 3.08, 2.96, 3.11, 3.07, 3.39, 3.02, 2.86, 3.1, 3.11]
22
20
42
15.9
19.22
35.13
4.4
0.388
Increased
7.8
Hyperplastic
0
0
0
0
Transabdominal
1
1
1
2
Letrozole
7.5
54.1
16.8
0
0
5
11.7
1
26
67.1
53.9
60.5
41.1
1
0.682
0
27.6
0
0
0
1
0
High
0
0
6.9
1
1
Combined_OCP_Spiro
Drospirenone
32
44.6
173.8
0
0
0
25
15.2
0
0
0
0
0
0.819
67
0
0
6.4
0
0
36.6
0.6
0
1
4.5
0
0
1
0
0
4.84
1
1
13
34.9
12.6
44.3
47.3
91.6
6.94
55
3
0
0
1
0
0
2
5
29,274
118,830
31,687
1,770
PCOS-0000002
26.4
Hispanic
164.6
80.3
29.6
Private
Urban
D
0
1
1
Oligomenorrhea
35
10.4
0
4.6
0
0
1
18.7
9.9
10.35
4.19
2.47
1.73
185.8
30
0.1
10
12.32
81.2
75
98.2
36.2
17.1
2.11
99.3
23
0.794
1.285
26.4
16.2
[11.52, 11.01, 9.79, 10.15, 8.29, 10.0, 9.95, 10.7, 9.52, 11.06, 11.87, 10.59, 10.88, 10.43, 10.35]
[10.0, 11.27, 10.0, 18.37, 16.29, 11.54, 10.0, 10.0, 14.76, 11.05, 11.92, 10.0, 13.71, 11.82, 10.0]
[2.01, 2.04, 1.88, 1.69, 1.6, 1.46, 1.42, 1.56, 0.63, 0.98, 0.94, 0.84, 0.59, 0.5, 0.5]
0
0
0
0
0
114.8
3.8
1.09
141.7
0.28
108.1
142.2
5.4
Prediabetes
0
0
16.41
38.6
557
2.65
3.34
104.5
1.041
210.5
124.6
47.5
192
163
78.7
131.9
4.1
3.69
6
131
96
1
5
1
0
[1.08, 0.85, 0.99, 1.39, 1.22, 0.95, 0.89, 1.1, 0.85, 0.95, 1.15, 1.32, 1.21, 0.63, 1.15]
15
16
31
18.48
7.44
25.92
6.2
0.45
Markedly_Increased
13.4
Hyperplastic
0
0
0
0
Transabdominal
1
1
0
0
null
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
Moderate
0
0
0
0
1
Metformin
null
0
0
0
1,000
1.5
0
0
0
0
0
0
0
1
0.966
25
1
0
3.6
0
0
30.5
0.645
4
0
3.5
0
0
0
1
0
3.54
1
0
18.9
50.2
13.1
38.7
20.2
86.8
6.22
84
3
0
1
1
1
0
2
2
5,744
105,942
25,989
4,206
PCOS-0000003
27.5
White
157.1
68.8
27.9
Medicaid
Suburban
A
1
1
1
Oligomenorrhea
35
10.4
1
13.6
0
1
0
27.5
2.7
4.85
7.36
0.66
2.42
149.4
68
0.1
67.5
25
78.1
164.4
180.7
101.4
28.1
7.32
199.9
18.4
3.538
1.167
18.1
51.4
[4.95, 5.09, 6.46, 3.58, 5.35, 4.81, 5.32, 3.6, 2.46, 2.0, 3.17, 4.16, 4.41, 7.75, 6.5]
[63.63, 68.87, 65.85, 66.34, 68.22, 69.96, 66.12, 71.74, 62.91, 67.51, 77.87, 68.37, 73.21, 67.85, 69.8]
[7.31, 7.17, 6.93, 7.05, 6.67, 6.85, 6.82, 6.55, 6.3, 6.33, 6.06, 6.19, 5.52, 5.69, 5.24]
1
0
1
0
0
75.6
26.5
4.94
143.8
0.28
98
51.4
4.5
NGT
1
0
21.1
36.1
332
2.03
0.86
82.2
0.848
219.7
132.3
58.8
143.4
161
105.3
37.1
5.25
1.28
1.84
139
75
0
1
0
0
[5.23, 4.96, 4.99, 5.25, 4.87, 4.75, 4.85, 5.03, 4.63, 5.07, 4.83, 5.17, 4.46, 4.78, 4.6]
14
18
32
14.66
14.44
29.09
7.5
0.43
Increased
11.1
Proliferative
0
0
0
0
Transvaginal
1
1
0
0
null
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
High
0
0
0
0
1
null
null
0
0
0
0
0
0
0
0
0
0
0
0
0
0.497
40
0
0
10.9
0
0
28
0.609
23
0
5.5
0
0
0
0
0
4.45
0
0
36
5
11.3
42.7
33.6
104.6
6.18
58
5
0
1
0
0
0
11
5
11,288
40,426
17,881
2,774
PCOS-0000004
19
East_Asian
159.9
76.9
30.1
Private
Suburban
A
1
1
1
Oligomenorrhea
35
10.4
1
7.8
0
0
0
19
3.3
11.97
1.63
7.36
2.3
182.4
86
0.69
73.4
25
78.6
234.8
153.2
109
35.2
2.76
218.5
11.1
0.123
1.102
27.1
25.9
[10.32, 12.85, 12.45, 10.67, 12.24, 13.79, 11.49, 9.44, 11.95, 10.62, 11.46, 11.85, 9.42, 9.55, 12.7]
[71.35, 63.18, 76.58, 74.53, 70.59, 68.17, 76.78, 74.84, 82.97, 75.12, 74.99, 72.77, 76.71, 75.94, 78.45]
[2.66, 2.56, 2.43, 2.56, 2.58, 2.07, 1.96, 1.99, 1.75, 1.87, 1.11, 1.28, 1.17, 0.74, 0.89]
1
1
0
0
0
83.6
15
3.09
148.3
0.28
111
87.4
4.8
NGT
1
1
7.14
24
437
1.58
3.66
87.5
0.849
187
116.9
50
101
137.1
68.9
14.1
2.49
1.25
3.5
137
55
0
2
0
0
[3.43, 3.19, 3.29, 2.91, 2.91, 3.22, 3.15, 3.25, 3.1, 3.19, 3.17, 3.29, 3.3, 2.81, 2.69]
19
20
39
10.77
8.25
19.01
8.3
0.467
Increased
10.5
Atrophic
0
0
0
0
Transvaginal
1
1
0
0
null
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
Moderate
0
0
0
0
1
OCP
Dienogest
76
62.3
254.4
0
0
0
0
0
0
0
0
0
1
0.662
4
1
1
8.4
0
0
37.7
0.608
0
0
4.5
0
1
0
1
0
5.2
0
1
28.1
55.5
12.8
30.2
22.4
96.2
6.46
88
6
0
0
0
0
1
5
5
28,882
85,919
26,221
2,454
PCOS-0000005
24.6
White
163.2
55.8
20.9
Private
Suburban
A
1
1
1
Oligomenorrhea
78.2
4.7
1
10.5
0
0
1
24.6
0.7
21.14
9.17
2.3
1.93
128.3
55.2
2.65
70.2
25
125.2
252.8
325.2
75.3
31.3
7.41
300
9.8
3.29
1.27
16.1
32
[18.23, 22.14, 19.66, 18.97, 21.05, 21.26, 20.1, 22.38, 19.12, 20.53, 20.26, 21.07, 21.56, 19.63, 22.22]
[70.48, 62.66, 62.39, 70.17, 69.34, 69.81, 70.11, 71.13, 74.01, 65.78, 65.54, 65.85, 71.38, 75.2, 68.5]
[6.91, 6.95, 7.01, 6.94, 6.85, 6.82, 6.63, 6.78, 6.32, 6.16, 6.31, 5.79, 6.05, 5.87, 5.7]
1
0
1
0
0
111.1
9
2.47
181.8
0.28
105
53.4
5.5
Prediabetes
0
0
8.99
31.5
456
1
3.68
89.1
0.807
162.5
63.6
65.6
166.5
96.9
83.6
31.2
1.64
3.5
7.26
116
80
1
3
0
0
[2.48, 2.56, 2.71, 2.8, 2.54, 2.59, 2.24, 2.46, 2.66, 2.65, 2.52, 2.65, 2.57, 2.71, 2.53]
16
19
35
6.43
16.37
22.8
3
0.334
Markedly_Increased
10.4
Proliferative
1
0
0
0
Transabdominal
1
1
0
0
null
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
High
0
0
0
0
1
Metformin
null
0
0
0
2,000
0.8
0
0
0
0
0
0
0
0
0.472
41
0
0
3
0
0
35.7
0.604
15
0
4.2
0
0
0
0
0
5.02
0
0
18.3
20.4
12.3
45.5
31.4
96.1
6.35
72
5
1
1
1
0
0
3
2
41,292
61,175
26,699
2,531
PCOS-0000006
32.3
South_Asian
163
69.4
26.1
Medicaid
Urban
A
1
1
1
Oligomenorrhea
48.8
7.5
0
6
0
0
0
28.4
0.8
9.23
7.45
1.24
1.75
34.1
72.9
1.36
90.4
25
90.4
189
168.4
53.1
35.4
4.11
204.1
26.7
3.966
1.303
16.7
33.3
[11.41, 8.54, 10.92, 8.26, 9.14, 7.62, 9.91, 11.39, 9.11, 8.93, 7.55, 8.88, 6.84, 7.86, 9.57]
[95.68, 101.64, 88.06, 96.15, 91.38, 89.8, 92.13, 90.65, 90.85, 88.77, 84.81, 84.23, 93.02, 89.3, 88.02]
[4.11, 4.15, 3.91, 3.62, 3.88, 3.83, 3.49, 3.47, 3.4, 3.26, 3.03, 2.91, 2.77, 2.33, 2.57]
1
0
1
1
0
75.7
7.6
1.43
159.1
0.28
128.5
219.2
4.6
NGT
0
0
11.04
31.7
408
2.41
2.07
86.7
1.007
182
97.5
52
162.5
130
85.3
57.6
5.16
3.7
3.01
90
67
0
1
0
0
[1.71, 1.4, 1.69, 1.44, 1.44, 1.41, 1.43, 1.77, 0.97, 1.03, 1.32, 1.43, 1.57, 1.52, 1.35]
20
20
40
14.79
17.12
31.91
8.8
0.392
Increased
9.3
Secretory
0
0
1
0
Transvaginal
1
1
1
3.6
Clomiphene
0
0
0
70.1
27.2
1
13.4
5
18
71.1
47
45.7
24.4
1
0.693
3
32.1
0
0
0
1
1
High
0
0
6.5
0
1
Combined_OCP_Spiro
Drospirenone
82
64.6
150.9
0
0
0
50
16.5
0
0
0
1
0
0.81
18
1
0
3.8
0
0
35.5
0.62
0
1
3.7
0
0
1
0
0
4.98
0
0
9.1
45.5
13.7
26.8
33.9
100.2
5.15
64
1
1
0
0
0
1
8
6
57,134
133,915
33,418
1,285
PCOS-0000007
28.5
Black
169.8
48.3
16.7
Private
Urban
B
1
1
0
Oligomenorrhea
51.3
7.1
1
19
1
0
0
22.9
2.2
17.98
4.61
3.9
1.82
73.1
93.1
0.26
74.1
25
101.2
183.1
259.7
112.5
35.9
6.64
169.7
87.4
8.887
0.7
5
37.6
[18.35, 15.99, 17.94, 20.98, 19.22, 18.23, 17.32, 17.39, 14.79, 18.37, 19.25, 15.62, 16.99, 16.24, 16.53]
[74.33, 65.78, 76.58, 77.13, 73.11, 64.2, 70.13, 79.05, 63.01, 72.73, 69.4, 77.34, 71.42, 75.73, 76.38]
[7.01, 6.48, 6.48, 5.99, 6.4, 5.89, 5.81, 5.8, 5.37, 5.61, 5.64, 5.38, 4.88, 5.06, 5.11]
1
1
1
1
1
70
5.4
0.93
146.3
0.28
115.9
154.7
4.9
NGT
0
1
14.63
52.1
379
0.86
3.01
77.3
0.852
222.6
129.8
75.1
88.4
147.5
75.4
126
2.12
5.69
0.92
123
95
0
1
0
0
[0.88, 0.9, 0.93, 0.91, 1.17, 0.64, 1.16, 0.91, 1.06, 0.76, 1.25, 1.23, 1.18, 0.68, 1.15]
9
3
12
6.95
7.73
14.68
16.7
0.269
Normal
9.9
Secretory
0
0
0
0
Transvaginal
0
1
1
0.6
null
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0.699
4
32.3
0
1
0
0
0
Low
0
0
7.1
1
0
null
null
0
0
0
0
0
0
0
0
0
0
0
0
1
0.866
0
0
0
11.4
0
0
38.9
0.621
0
1
3.5
0
0
0
0
0
3.93
0
1
10.2
17.6
10.8
34.6
26
82.1
2
63
6
1
1
0
1
0
9
9
89,829
52,880
27,549
1,841
PCOS-0000008
38.3
South_Asian
165.5
119
43.4
Medicaid
Urban
C
1
0
1
Regular
25.1
13
0
4.1
0
0
1
21.7
1.7
2
7.22
0.3
1.15
166.8
95.7
14.82
103.3
25
62.7
69.2
208.6
71.9
51
2.86
158.5
12.7
3.133
1.42
7.8
31.9
[2.0, 2.0, 2.0, 2.0, 2.0, 2.0, 2.48, 2.0, 3.07, 2.0, 2.0, 2.0, 3.99, 2.5, 2.0]
[105.27, 94.84, 103.1, 111.26, 103.8, 103.54, 105.46, 106.85, 95.28, 96.54, 104.11, 100.41, 108.52, 102.01, 95.53]
[2.6, 2.19, 2.57, 2.46, 2.29, 2.47, 2.38, 1.98, 1.47, 1.9, 1.77, 1.6, 1.61, 1.06, 1.58]
1
0
0
0
0
90.7
30.2
6.77
48.9
0.28
115.1
297.6
5
NGT
1
0
9.12
40
460
2.33
1.9
94.2
0.928
181.9
111
28.7
210.9
153.2
91.1
49.5
3.6
3.09
5.81
142
82
1
4
0
1
[6.6, 6.54, 6.58, 6.64, 6.53, 6.8, 6.91, 6.45, 6.77, 6.72, 6.83, 6.76, 6.47, 6.51, 6.77]
19
6
25
14.9
17.43
32.32
7.5
0.448
Markedly_Increased
8.6
Secretory
0
0
1
0
Transvaginal
1
1
0
0
null
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
Moderate
0
0
0
0
1
OCP
Cyproterone
48
47
191.3
0
0
0
0
0
0
0
0
0
1
0.782
105
0
0
9.3
0
0
38.7
0.798
91
0
6.4
0
0
1
0
0
4.18
0
0
18.3
56.7
10.7
66.8
44.4
86.3
4.9
81
1
1
1
0
0
1
7
3
28,830
95,849
23,818
422
PCOS-0000009
15.7
South_Asian
162.3
77.3
29.3
Uninsured
Urban
B
1
1
0
Oligomenorrhea
35
10.4
0
3.8
0
0
0
15.7
1.1
12.86
2.27
5.67
1.92
61.2
102.4
0.39
96.6
25
89.5
191.9
203.2
10
19.7
1.46
157.6
13.5
4.5
0.855
12.8
13
[12.16, 16.42, 10.26, 13.17, 11.17, 12.12, 13.08, 9.37, 13.22, 15.72, 12.18, 13.25, 14.4, 12.62, 11.99]
[87.48, 99.15, 96.13, 92.53, 97.09, 94.25, 94.47, 99.01, 91.23, 100.77, 90.99, 93.93, 104.28, 101.09, 96.97]
[1.27, 1.23, 1.23, 1.1, 0.96, 0.85, 0.69, 0.5, 0.5, 0.56, 0.5, 0.5, 0.5, 0.5, 0.5]
1
1
0
0
0
111
19.4
5.31
78
0.28
128
93.3
5.4
Prediabetes
1
0
9.54
41.5
313
1.14
1.91
81.1
0.758
290
189.7
68.1
178
221.9
71
70.4
1.59
2.27
1.48
105
76
0
2
1
0
[5.12, 5.87, 5.22, 5.32, 5.05, 5.65, 5.53, 5.37, 5.04, 5.35, 5.08, 5.6, 5.47, 5.33, 4.82]
5
10
15
9.43
9.22
18.64
10.2
0.275
Normal
12
Proliferative
1
0
0
0
Transvaginal
0
1
0
0
null
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
Low
0
0
0
0
1
GLP1_RA
null
0
0
0
0
0
0
0
0
1
5.1
23.9
0
1
0.522
29
0
0
6.7
0
0
40.9
0.655
16
0
5.7
0
0
1
1
0
4.42
0
0
15
64.6
11.7
42.2
40
105.8
4.17
62
1
0
0
1
1
1
8
4
58,825
49,898
30,219
2,673
PCOS-0000010
32.6
Hispanic
164.1
101.5
37.7
Marketplace
Rural
A
1
1
1
Oligomenorrhea
36
10.1
0
1.6
0
0
0
30.4
7.9
23.04
8.35
2.76
1.94
99
30
2.01
52
25
82.3
363.8
192.6
85.1
10
7.17
121.5
18.1
0.836
1.133
12.5
10
[22.37, 21.43, 22.21, 24.65, 23.95, 22.85, 23.97, 21.3, 23.09, 23.27, 22.34, 23.7, 21.87, 23.81, 23.87]
[40.37, 56.8, 39.85, 49.58, 56.14, 50.77, 46.18, 47.67, 56.15, 44.35, 56.56, 51.82, 47.27, 49.71, 47.97]
[7.34, 7.19, 6.58, 6.73, 6.51, 6.83, 6.18, 6.65, 6.2, 5.85, 5.83, 5.69, 5.47, 5.63, 5.24]
0
1
1
0
0
71.7
16.9
2.99
54.1
0.28
108.2
119.8
4.5
NGT
1
0
10.01
40.1
178
1.57
3.65
85.7
0.816
176.4
109.8
44.7
109.4
131.7
100.7
38.8
3.33
2.54
4.91
129
80
0
1
0
0
[2.94, 2.93, 3.01, 3.33, 2.72, 3.14, 2.61, 3.03, 3.3, 3.09, 3.02, 2.88, 3.0, 2.94, 2.83]
16
18
34
12.85
12.73
25.58
3.9
0.44
Increased
9.7
Hyperplastic
0
0
0
0
Transabdominal
1
1
0
0
null
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
High
0
0
0
0
0
null
null
0
0
0
0
0
0
0
0
0
0
0
1
1
0.81
0
0
0
7.8
0
0
34
0.606
4
1
4.5
0
0
0
0
0
4.31
0
1
23.7
25.7
14
28
35.9
106.6
7.18
95
2
1
0
0
1
0
3
6
16,876
180,000
25,269
3,046
PCOS-0000011
15.3
South_Asian
164.9
58.2
21.4
Uninsured
Urban
B
1
1
0
Oligomenorrhea
40.1
9.1
1
10.6
1
0
1
15.3
0.6
14.28
2.93
4.88
1.83
136
107.2
1.06
75.8
25
96.7
77.5
165.1
100.4
33.9
0.5
98.7
9.2
2.761
1.357
16.8
37.8
[15.46, 15.59, 13.08, 11.57, 16.6, 14.67, 11.71, 13.21, 15.44, 13.86, 13.51, 16.38, 12.71, 13.09, 14.6]
[77.36, 77.78, 79.44, 76.59, 77.76, 74.76, 76.05, 76.23, 76.66, 78.89, 78.02, 75.98, 72.56, 76.07, 75.69]
[0.54, 0.82, 0.5, 0.5, 0.5, 0.5, 0.5, 0.5, 0.5, 0.5, 0.5, 0.5, 0.5, 0.5, 0.5]
1
1
0
0
0
90.9
11.3
2.54
201.1
0.28
118.7
86.8
4.9
NGT
1
0
15.75
24.2
413
1.45
3.38
69.6
0.816
218.2
130
58
151.2
160.2
73.8
108.1
1.72
1.17
6.1
127
82
0
1
1
0
[2.2, 2.4, 2.42, 2.37, 2.33, 2.48, 2.3, 2.61, 2.56, 2.64, 2.65, 2.67, 2.47, 2.97, 2.59]
2
4
6
3.52
7.03
10.55
14.6
0.237
Normal
15
Hyperplastic
0
0
0
0
Transvaginal
0
1
1
0.8
Clomiphene
0
0
0
40.7
16.7
1
14.3
0
0
0
0
0
0
0
0.656
4
27.7
0
0
0
0
0
Low
0
0
3.4
1
0
null
null
0
0
0
0
0
0
0
0
0
0
0
0
0
0.582
0
0
0
3.9
0
0
28.7
0.661
0
1
4.3
0
0
1
1
0
5.14
0
0
23.7
22.6
10.9
29.2
31.1
111
4.33
75
5
1
1
0
0
1
12
6
5,455
78,755
27,388
3,489
PCOS-0000012
26.5
Hispanic
167.4
71.6
25.5
Private
Urban
A
1
1
1
Amenorrhea
35
10.4
1
16.9
0
0
1
26.5
0.9
16.29
6.23
2.62
1.65
142.4
112.5
5.06
90.2
25
123.9
327.7
125.2
102.3
41.4
9.51
156.5
48.9
1.612
0.7
13.4
32.4
[19.2, 16.31, 18.23, 16.68, 17.53, 16.71, 18.35, 16.38, 17.04, 16.84, 15.86, 16.9, 19.64, 15.89, 16.92]
[95.24, 94.77, 90.25, 80.67, 92.27, 81.33, 96.08, 90.88, 94.2, 86.6, 83.99, 91.25, 90.07, 88.24, 90.54]
[10.06, 9.55, 9.48, 9.32, 9.32, 8.87, 8.38, 8.63, 8.71, 8.23, 8.27, 8.05, 8.37, 8.1, 7.96]
1
1
1
1
0
99.5
13.7
3.36
125.9
0.28
83.9
30
5.3
NGT
1
0
16.84
46
557
0.7
2.08
87.4
0.72
214.4
108.4
63.2
214
151.2
72.3
116.3
2.14
3.66
6.69
113
55
0
1
1
0
[3.37, 3.35, 3.31, 3.52, 3.06, 3.26, 3.5, 3.24, 3.04, 3.5, 3.59, 3.36, 2.97, 3.51, 3.03]
19
15
34
12.37
14.53
26.9
7.5
0.388
Increased
7.7
Atrophic
0
0
0
0
Transvaginal
1
1
1
0.6
Letrozole
7.5
57.7
23
0
0
5
21.3
1
18
80.9
65.9
47.8
39.1
1
0.676
1
28.6
0
1
1
0
0
Critical
0
0
38.4
1
1
Clomiphene
null
0
0
0
0
0
0
0
0
0
0
0
1
0
0.453
37
1
0
5.7
0
0
34.3
0.623
28
0
4.7
0
1
0
0
0
3.6
0
0
5
5
11.3
25.7
32.5
68.6
4.93
68
3
0
1
0
0
1
9
6
21,632
19,801
28,811
1,597
PCOS-0000013
21.8
East_Asian
163.7
75.8
28.3
Private
Urban
B
1
1
0
Amenorrhea
43.9
8.3
1
16.4
0
0
0
21.8
0.3
11.26
7.96
1.41
1.29
130.7
69.3
0.3
88.4
25
89.3
330.7
249.1
140.9
39.2
6.6
109.7
22.2
5.327
1.203
24.6
34.7
[10.94, 13.93, 10.94, 8.56, 14.1, 12.28, 11.15, 10.7, 12.88, 10.45, 12.98, 12.07, 11.63, 11.48, 11.0]
[92.63, 84.98, 81.96, 90.9, 90.97, 90.37, 90.08, 87.16, 91.6, 88.26, 86.5, 87.2, 96.53, 81.51, 90.44]
[6.27, 6.46, 6.28, 5.83, 6.2, 5.93, 5.46, 5.93, 5.93, 5.82, 5.48, 5.29, 5.43, 5.38, 5.15]
1
0
1
0
1
81.5
16.5
3.31
131.5
0.28
80
164.5
5.2
NGT
1
1
17.58
33.8
386
1.89
1.65
76
0.699
234.1
150.1
41.5
212.8
192.7
89.3
85.8
4.16
4.35
6.38
123
83
0
2
0
0
[3.46, 3.5, 3.04, 3.2, 3.61, 3.42, 2.98, 3.57, 3.25, 3.64, 3.34, 3.4, 3.6, 3.18, 3.16]
7
10
17
4.34
3.66
8
17.5
0.23
Normal
7.8
Hyperplastic
0
0
0
0
Transvaginal
0
0
1
2.4
FSH_injection
0
0
0
0
0
0
0
3
25
83.7
48.5
61.9
50.6
0
0.757
2
35.7
0
0
1
0
0
Moderate
0
0
20.1
1
0
null
null
0
0
0
0
0
0
0
0
0
0
0
1
0
0.962
0
0
0
4.8
1
0
35.1
0.645
0
0
4.7
0
0
0
1
0
3.54
0
1
24.7
63.7
12.2
47.1
31.5
96.6
7.79
81
1
0
1
0
0
0
2
5
10,558
134,480
18,603
789
PCOS-0000014
25.4
East_Asian
165.8
95.3
34.7
Medicaid
Urban
D
0
1
1
Amenorrhea
35
10.4
0
3.6
0
0
0
25.4
8.9
2
6.1
0.33
1.75
97.3
91.4
0.1
46.4
25
75.2
216.5
125.5
23
16.6
6.67
186.3
13.1
0.118
1.054
13.8
17.1
[4.76, 2.0, 2.0, 2.0, 4.59, 2.0, 2.0, 2.0, 2.0, 2.0, 5.69, 4.09, 2.0, 2.97, 2.0]
[39.26, 50.45, 51.01, 50.55, 44.49, 45.7, 49.37, 47.94, 44.8, 39.89, 46.83, 50.69, 41.58, 48.92, 47.7]
[6.82, 6.72, 6.29, 5.99, 6.08, 6.25, 5.84, 5.69, 5.34, 5.94, 5.63, 5.5, 5.42, 5.22, 4.94]
0
0
1
0
0
95.1
15.6
3.67
189
0.28
134.8
140
5.2
NGT
1
0
16.13
29.2
412
2.86
3.72
93.6
0.974
187.7
112.8
42.5
162.4
145.3
125.9
61.2
2.73
7.93
5.23
132
77
1
4
0
1
[3.61, 3.86, 3.84, 3.47, 3.5, 3.69, 4.01, 3.28, 3.72, 3.39, 3.54, 3.59, 3.58, 3.56, 3.67]
15
11
26
17.34
17.26
34.6
10.5
0.343
Markedly_Increased
11
Proliferative
0
0
0
0
Transvaginal
1
1
0
0
null
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
High
0
0
0
0
0
null
null
0
0
0
0
0
0
0
0
0
0
0
0
0
0.686
0
0
0
8.9
0
0
29.3
0.722
9
1
4.8
0
1
0
0
0
2.94
0
0
21.9
65.6
12.9
49.5
16.6
77.8
4.95
57
4
0
1
0
1
1
9
6
61,405
73,260
27,558
2,228
PCOS-0000015
25.7
White
158.5
78.5
31.2
Private
Urban
D
0
1
1
Oligomenorrhea
35
10.4
0
5.6
0
0
1
25.7
1.1
6.97
7.54
0.92
1.42
175
55
0.1
37.7
25
75.1
163.3
198.6
81
10
7.86
153.3
86.5
4.397
1.428
11.7
30.7
[6.0, 5.95, 8.32, 8.17, 7.38, 4.94, 6.5, 5.85, 8.27, 8.73, 8.55, 5.83, 2.86, 4.32, 9.1]
[36.09, 34.69, 44.26, 42.75, 37.79, 36.52, 37.16, 38.6, 44.09, 39.38, 40.6, 42.37, 33.01, 40.71, 36.51]
[7.36, 7.31, 7.42, 7.61, 7.4, 7.3, 7.53, 6.77, 6.89, 6.84, 6.51, 6.55, 6.1, 6.58, 6.04]
0
0
1
1
0
119.7
17.1
5.06
144.1
0.28
117.2
153.4
5.6
Prediabetes
1
0
12.01
25.9
362
1.35
5.76
87.9
0.789
166
84.6
52.1
147.1
114
85.3
78.1
3.51
8.57
5.03
145
78
0
2
0
0
[4.91, 4.82, 5.52, 5.22, 4.99, 5.31, 5.2, 5.45, 4.75, 5.01, 4.97, 4.66, 5.27, 5.0, 5.21]
27
16
43
14.09
15.71
29.81
11
0.392
Increased
12.2
Secretory
0
0
0
0
Transvaginal
1
1
1
0.2
Letrozole
2.5
57.6
31.2
0
0
6
9.6
0
0
0
0
0
0
0
0.834
4
23.9
0
1
0
0
0
High
0
0
21
0
1
OCP
Drospirenone
48
53.9
256.9
0
0
0
0
0
0
0
0
1
0
0.836
24
1
1
8.4
0
0
37
0.645
23
1
5.5
0
0
1
0
0
5.47
0
0
8.7
34.8
10.7
33.1
49.7
81.6
4.73
78
2
0
1
0
0
1
11
7
25,821
47,216
19,331
4,845
PCOS-0000016
42.1
Other
170.4
63.6
21.9
Private
Suburban
A
1
1
1
Oligomenorrhea
63.8
5.7
1
16.9
0
0
1
19.5
0.6
17.74
4.17
4.26
1.46
115
78.5
1.82
73.8
25
82.8
150.1
240
89.3
36.9
7.87
193.3
7.6
3.002
1.213
12.3
21.7
[19.64, 19.34, 18.55, 20.7, 17.46, 22.29, 17.4, 18.13, 17.15, 18.3, 19.0, 17.57, 20.41, 18.1, 18.15]
[70.18, 75.49, 73.28, 71.38, 70.71, 84.5, 72.76, 67.98, 71.02, 73.61, 76.0, 76.03, 76.52, 71.23, 75.17]
[7.69, 7.62, 7.44, 7.27, 7.6, 7.4, 7.34, 7.03, 7.06, 6.43, 6.84, 6.58, 6.55, 6.38, 5.99]
1
1
1
0
0
74
8.3
1.52
136.9
0.28
125.2
47.9
4.5
NGT
0
1
10.57
14.5
258
0.84
2.6
66.8
0.704
191.4
113.8
39
192.9
152.4
110.5
47.3
4.25
3.08
5.71
124
73
0
2
1
0
[1.77, 1.46, 1.58, 1.56, 1.71, 1.36, 1.77, 1.66, 1.3, 1.81, 2.01, 1.77, 1.85, 1.58, 1.24]
10
18
28
13.59
12.62
26.2
7.8
0.451
Markedly_Increased
7.7
Hyperplastic
1
0
0
0
Transvaginal
1
1
1
0.4
Clomiphene
0
0
0
40.3
20.3
2
16.9
0
0
0
0
0
0
0
0.802
0
30.9
0
0
0
0
0
High
0
0
1.4
1
1
Metformin
null
0
0
0
1,000
0.95
1
0
0
0
0
0
1
0
0.519
31
1
1
8.1
0
0
32.3
0.686
95
0
3.8
0
0
1
0
0
3.17
0
1
16.5
40.5
12.2
40.7
22.7
101.2
6.13
75
3
1
0
0
0
1
20
6
53,084
41,082
22,469
3,180
PCOS-0000017
29
South_Asian
170.9
99.7
34.1
Private
Suburban
A
1
1
1
Amenorrhea
37.2
9.8
1
14.3
0
0
0
29
0.6
14.09
5.43
2.6
1.82
74.3
106.7
3.73
46.3
25
70.9
254.5
203.1
67.7
34.9
3.8
90.5
16.7
1.921
1.244
19.2
17
[14.73, 15.33, 12.89, 13.58, 10.04, 13.16, 13.31, 12.57, 14.34, 14.01, 10.71, 14.42, 12.7, 14.82, 12.17]
[46.41, 45.16, 47.5, 46.79, 45.27, 40.14, 40.38, 43.95, 46.26, 43.86, 48.79, 45.17, 42.43, 45.18, 47.19]
[3.87, 4.06, 3.43, 3.43, 3.41, 3.2, 2.98, 2.65, 2.74, 2.51, 2.26, 2.32, 2.15, 2.36, 2.24]
0
1
1
0
0
86.2
17
3.62
54.1
0.28
111.9
192.2
5.1
NGT
1
0
14.3
20.3
237
2.58
5.27
96.9
1.014
169.3
130.3
28
55.7
141.4
89.2
24.3
3.69
7.47
4.16
142
80
1
3
0
0
[3.43, 4.19, 3.7, 3.7, 3.73, 4.0, 3.78, 3.3, 3.9, 3.56, 3.64, 3.37, 3.73, 3.49, 3.64]
14
23
37
20.09
14.28
34.37
8.2
0.401
Markedly_Increased
8
Secretory
0
0
1
0
Transvaginal
1
1
0
0
null
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
High
0
0
0
0
1
Combined_Met_OI
null
0
0
0
500
0.53
0
0
0
0
0
0
0
0
0.591
50
0
0
11.3
0
0
41.4
0.71
51
0
4.8
0
0
1
0
0
3.92
0
1
19.3
63.8
12.7
54.5
45.7
85.8
6.92
73
6
0
0
0
0
0
9
6
19,602
31,858
30,379
2,605
PCOS-0000018
31.1
White
163.3
76.2
28.6
Private
Rural
A
1
1
1
Amenorrhea
35
10.4
1
11.6
0
0
0
27.9
0.7
15.76
6.44
2.45
1.29
108.2
70.7
0.23
54.5
25
99.2
223.2
271.8
39.3
31.8
7.38
171.5
21.6
1.287
1.014
8.9
40.4
[17.15, 15.38, 15.44, 16.37, 16.63, 14.52, 16.84, 15.93, 13.88, 15.5, 17.83, 18.27, 16.84, 13.97, 16.5]
[57.94, 57.44, 57.68, 55.99, 54.25, 52.1, 46.95, 55.9, 55.28, 56.77, 49.19, 57.12, 62.76, 54.85, 54.29]
[7.44, 7.67, 6.94, 7.06, 6.74, 6.67, 6.65, 6.81, 6.78, 6.39, 6.1, 6.56, 5.85, 5.71, 5.35]
0
0
1
0
0
108.9
21.9
5.9
192.2
0.28
80
218.9
5.5
Prediabetes
1
1
5.34
46.8
477
1.49
3.3
78.3
0.868
203
146.1
33.3
117.8
169.7
114.1
36.6
2.14
5.01
2.26
106
87
1
3
0
0
[5.96, 5.77, 6.2, 6.08, 6.1, 6.19, 5.82, 5.93, 5.92, 5.69, 5.9, 6.22, 6.0, 5.68, 5.64]
24
17
41
13.27
14.39
27.66
3.6
0.491
Markedly_Increased
13.1
Proliferative
0
0
0
0
Transvaginal
1
1
0
0
null
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
High
0
0
0
0
1
Metformin
null
0
0
0
1,000
1.25
0
0
0
0
0
0
1
0
0.721
19
1
1
8
0
0
28.9
0.708
27
0
6
0
0
1
0
0
3.41
1
0
10.7
31.7
11.5
36.9
41.2
74
5.04
68
5
1
1
0
0
0
9
6
36,505
47,283
28,846
2,772
PCOS-0000019
30
South_Asian
162.3
87
33
Marketplace
Urban
B
1
1
0
Amenorrhea
60.2
6.1
1
23.4
0
0
0
27.2
1.7
11.56
8.59
1.35
1.42
20
111.5
0.11
67.8
25
71.4
123
174.5
10
36.3
9.8
69.8
42.4
1.986
1.143
13
25.6
[12.16, 8.88, 10.89, 12.7, 12.01, 12.45, 11.46, 13.31, 12.95, 12.23, 12.95, 12.69, 10.9, 9.54, 12.19]
[69.97, 72.15, 64.04, 64.16, 69.63, 67.5, 60.24, 69.29, 60.38, 64.01, 73.19, 75.09, 62.92, 66.47, 67.96]
[10.16, 9.58, 9.46, 9.75, 9.24, 9.34, 8.78, 8.92, 8.51, 8.51, 8.77, 8.47, 8.3, 8.09, 8.08]
1
0
1
1
0
100.1
26.4
6.53
32.2
0.28
103
173.5
5.2
Prediabetes
1
0
11.37
31.8
313
1.76
4.56
83.5
0.875
215.2
116.7
64.2
171.8
151
114.8
152.7
3.09
3.58
3.33
136
82
1
3
0
0
[6.33, 6.95, 6.49, 6.37, 6.81, 6.58, 6.64, 6.5, 6.46, 6.49, 6.25, 6.51, 6.58, 6.9, 6.54]
2
7
9
12.48
8.73
21.21
12.6
0.29
Normal
6.8
Hyperplastic
0
0
1
0
Transabdominal
0
1
1
2.4
GnRH_pump
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0.639
3
32.1
0
1
1
0
0
Moderate
0
0
9.7
1
1
Metformin
null
0
0
0
1,000
1.2
1
0
0
0
0
0
1
1
0.636
6
1
0
5.9
0
0
28
0.785
39
1
6.3
0
0
1
1
0
3.15
0
1
6.6
5.1
14.4
83.2
38.8
66.2
3.47
73
3
0
1
1
0
1
3
6
40,307
107,943
17,829
1,043
PCOS-0000020
33.3
East_Asian
171.4
104.7
35.6
Medicaid
Suburban
D
0
1
1
Oligomenorrhea
87.5
4.2
0
4.4
0
0
0
24.5
0.2
20.19
5.4
3.74
1.73
91.2
30
0.1
72.2
25
45
155.6
127.6
43.7
41.8
6.33
157.6
17.9
1.205
1.535
19.1
22.5
[18.98, 18.69, 18.62, 19.26, 18.63, 17.84, 20.51, 20.54, 22.74, 19.18, 20.63, 20.65, 19.8, 21.3, 21.35]
[73.53, 71.2, 70.79, 66.75, 69.0, 69.73, 67.73, 73.98, 77.01, 68.59, 73.36, 68.09, 71.0, 69.46, 74.63]
[6.2, 6.42, 6.05, 5.84, 5.6, 5.79, 5.79, 5.55, 5.82, 5.54, 5.07, 4.95, 4.99, 4.61, 4.89]
1
1
1
0
0
104.2
23.9
6.16
124.8
0.28
167.6
199.4
5.3
Prediabetes
1
0
12.91
33.2
341
2.45
4.12
80.1
0.994
174
110.5
36.4
135.1
137.6
112.6
58.3
2.24
3.6
5.27
136
75
1
3
0
0
[6.16, 6.02, 6.13, 6.18, 6.13, 6.15, 5.87, 5.97, 6.13, 6.13, 6.05, 6.13, 6.17, 6.34, 6.14]
18
14
32
16.62
16.03
32.64
10.6
0.456
Increased
8.7
Secretory
1
0
1
0
Transvaginal
1
1
0
0
null
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
High
1
0
0
0
1
Spironolactone
null
0
0
0
0
0
0
200
25.6
0
0
0
0
0
0.899
54
1
1
7.2
0
0
28
0.736
78
1
6.1
0
0
0
1
0
1.78
1
0
29.4
64.4
12.8
59.3
48.1
78.4
6.94
67
2
1
1
0
1
0
10
3
49,389
70,005
23,478
1,687
PCOS-0000021
35.1
White
158.7
77.5
30.8
Private
Rural
C
1
0
1
Regular
28.8
12.7
1
25.8
0
0
0
21
0.7
2
7.19
0.3
0.76
64.8
92.6
18.69
115.1
25
80.1
111.3
196.2
152.7
33.8
4.4
142.3
28.4
0.606
0.864
14.6
31.6
[2.0, 2.0, 2.76, 3.59, 2.91, 2.11, 2.0, 2.0, 2.0, 2.61, 2.5, 2.0, 2.0, 3.81, 2.12]
[109.47, 124.56, 115.02, 116.68, 116.74, 113.67, 112.23, 123.63, 119.15, 118.43, 117.44, 111.13, 120.25, 111.77, 116.27]
[4.07, 3.87, 4.23, 3.88, 3.53, 3.91, 4.11, 3.84, 3.39, 3.32, 3.38, 3.31, 2.89, 2.85, 2.78]
1
0
1
1
0
101.4
15.7
3.93
110.8
0.28
147.3
223.4
5.4
Prediabetes
1
0
9.41
49.7
433
4.39
1.49
81.5
0.813
207.6
103.4
69.4
173.7
138.2
111.6
146.5
1.61
8.57
6.17
130
80
0
2
1
0
[4.06, 3.94, 3.76, 3.72, 3.78, 3.98, 3.93, 3.98, 4.03, 3.81, 4.23, 3.88, 3.85, 4.03, 3.57]
13
20
33
9.11
17.67
26.78
12.5
0.402
Increased
12.4
Secretory
0
0
0
0
Transvaginal
1
1
1
0.1
Letrozole
2.5
53.3
29.5
0
0
0
0
0
0
0
0
0
0
0
0.584
3
28.8
0
0
0
0
0
High
0
0
5
0
1
Metformin
null
0
0
0
1,000
1.48
0
0
0
0
0
0
1
0
0.66
62
0
0
8.3
0
0
50.5
0.712
4
1
5
0
0
0
1
1
3.66
0
1
7.9
95.5
11.9
44.9
20.8
92.1
4.92
71
6
0
0
0
0
1
14
7
55,874
79,293
25,145
1,637
PCOS-0000022
35.9
White
156.7
62.3
25.3
Medicaid
Urban
D
0
1
1
Oligomenorrhea
57
6.4
0
1.1
0
0
1
20.3
0.9
10.25
7.19
1.43
1.35
133.6
70.7
0.93
39.1
25
83.3
316.4
151.1
96.9
14.3
5.01
59.7
25
1.492
1.643
21.3
10
[10.05, 9.54, 8.26, 13.16, 10.72, 10.96, 9.21, 11.33, 9.68, 9.82, 11.16, 7.8, 12.64, 10.52, 12.17]
[34.76, 35.37, 34.42, 40.06, 39.33, 37.21, 35.01, 34.0, 38.87, 37.2, 36.32, 45.25, 38.73, 44.14, 36.93]
[5.06, 4.88, 4.43, 4.93, 4.5, 4.56, 4.14, 4.14, 3.88, 4.18, 3.87, 3.76, 3.84, 3.68, 3.48]
0
0
1
0
0
74.9
8.4
1.56
89.9
0.28
126
140.2
4.5
NGT
0
0
6.02
29.6
234
1.92
2.95
101.4
0.971
162
78.1
60.2
118.9
101.8
70.8
85.4
2.44
0.94
3.7
103
80
0
1
1
0
[1.56, 1.41, 1.51, 1.29, 1.64, 1.68, 2.05, 1.44, 1.51, 1.45, 1.6, 1.64, 1.55, 1.78, 1.44]
20
18
38
14.47
13.56
28.03
15.3
0.379
Markedly_Increased
6.7
Proliferative
0
0
0
0
Transabdominal
1
1
0
0
null
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
High
0
0
0
0
0
null
null
0
0
0
0
0
0
0
0
0
0
0
1
0
0.783
0
0
0
1.6
0
0
42.5
0.64
68
1
3.8
0
0
1
1
0
4.29
0
1
27.8
51.2
12.6
30.8
11.3
71
6.15
74
4
1
1
1
0
1
13
6
47,536
29,605
26,832
891
PCOS-0000023
20.3
Black
156.2
86.3
35.4
Private
Urban
D
0
1
1
Amenorrhea
47.2
7.7
0
2.6
0
0
0
20.3
0.3
22.91
8.75
2.62
1.91
112.6
59.1
0.1
55.1
25
81.8
223.3
54.6
112.2
10.7
7.3
167.5
63.9
2.077
1.278
18.6
40.5
[21.56, 19.25, 22.19, 24.05, 22.38, 24.11, 23.13, 24.84, 22.46, 23.61, 23.66, 25.16, 20.35, 22.22, 24.18]
[61.28, 56.06, 53.92, 58.12, 58.57, 53.66, 56.42, 59.82, 62.66, 58.07, 55.27, 54.88, 57.32, 54.63, 55.85]
[7.08, 7.44, 6.83, 6.85, 6.84, 7.09, 6.49, 6.32, 6.23, 6.55, 5.53, 5.78, 6.4, 5.85, 5.39]
1
1
1
1
0
96.3
19.4
4.61
135.7
0.28
162.6
189.7
5.1
NGT
1
1
7.39
25.9
188
0.73
2.15
81.7
0.824
135.6
94.7
20
104.3
115.6
86.6
40
2.55
7.25
3.83
123
71
0
1
0
0
[4.7, 4.61, 4.47, 4.86, 4.75, 4.57, 4.69, 4.65, 4.49, 4.68, 4.54, 4.47, 4.34, 4.59, 4.78]
14
27
41
17.85
19.1
36.95
10.4
0.513
Markedly_Increased
3
Hyperplastic
0
0
0
0
Transvaginal
1
1
1
0.9
Letrozole
7.5
62.8
24.4
0
0
2
12.5
1
21
60
53.4
58.6
55
1
0.337
2
29.4
0
0
1
0
0
High
0
0
15
1
1
Metformin
null
0
0
0
1,000
1.27
0
0
0
0
0
0
0
0
0.387
27
1
1
1
0
0
32.4
0.64
20
1
5.3
0
0
0
1
0
3.81
1
0
16.7
19.4
13.9
56.2
37.4
85.1
6.14
74
3
1
0
0
1
1
1
6
46,450
31,081
21,956
2,272
PCOS-0000024
21.1
South_Asian
174.2
90.1
29.7
Private
Urban
C
1
0
1
Regular
29.5
12.4
1
18.4
0
0
1
21.1
0.7
5.3
8.31
0.64
1.32
51.7
91
12.34
74.6
25
94.2
182
141.6
76.4
30.3
5.63
247.5
2.7
2.214
1.345
5.6
10
[5.15, 7.01, 3.98, 5.82, 6.57, 4.63, 4.66, 5.34, 6.11, 5.28, 6.76, 4.6, 3.3, 8.26, 4.39]
[72.37, 74.38, 74.91, 73.1, 74.57, 74.48, 75.34, 65.21, 82.17, 74.05, 76.97, 69.13, 72.76, 71.95, 80.52]
[5.51, 5.66, 5.26, 5.18, 5.1, 5.29, 4.53, 4.53, 4.28, 4.33, 4.27, 3.99, 4.04, 3.67, 3.75]
1
0
1
0
0
107.5
18.3
4.87
123.4
0.28
90.7
46.2
5.2
Prediabetes
1
1
15.05
41.8
455
1.02
2.7
84
0.893
197.4
114.4
33.5
247.5
163.9
115.6
16
1.93
3.47
0.5
128
84
1
3
0
0
[4.94, 4.74, 4.85, 5.35, 4.94, 4.68, 4.96, 4.65, 4.68, 4.71, 4.83, 5.11, 5.04, 5.03, 4.7]
14
17
31
12.8
13.85
26.66
9.3
0.403
Increased
13.8
Atrophic
0
0
1
0
Transvaginal
1
1
1
4.8
Letrozole
5
64.5
25.3
0
0
2
15.3
0
0
0
0
0
0
0
0.902
4
33.9
0
1
1
0
0
High
0
0
14.6
0
1
OCP
Drospirenone
55
46.9
147.4
0
0
0
0
0
0
0
0
1
0
0.588
14
1
0
3.7
0
0
28
0.669
0
1
5.4
0
0
0
0
0
4.17
0
1
26
57.6
11.8
46.6
20.4
110.2
8.46
76
1
0
1
0
0
1
6
3
43,162
38,528
26,698
1,737
PCOS-0000025
34.9
Other
166.9
71.3
25.6
Medicaid
Suburban
D
0
1
1
Oligomenorrhea
58.9
6.2
0
1.1
0
0
1
17.4
1.1
15.95
6.05
2.64
1.3
74.6
82.3
1.27
36.8
25
102
35.2
126.1
51.8
11.2
7.57
239.3
6.6
1.841
1.307
17.4
10
[16.59, 14.73, 16.4, 17.12, 14.04, 13.83, 18.46, 16.48, 15.32, 14.55, 15.18, 14.16, 17.27, 14.78, 17.59]
[35.18, 32.6, 35.07, 26.28, 36.29, 36.1, 40.08, 29.23, 41.43, 40.06, 41.79, 36.57, 40.83, 30.89, 39.63]
[7.42, 7.12, 7.11, 7.21, 6.93, 7.05, 6.49, 6.31, 6.89, 6.67, 6.16, 6.25, 6.34, 6.1, 5.92]
0
1
1
0
0
105.1
8.2
2.12
120.9
0.28
109.6
113.6
5.3
Prediabetes
0
0
12.14
19.9
480
0.72
2.24
79.7
0.8
170.6
99.7
60.9
50
109.7
114.4
44.9
5.37
3.17
5.98
119
80
0
1
0
0
[1.98, 1.92, 1.99, 2.14, 2.07, 2.26, 2.38, 1.92, 1.97, 1.83, 2.52, 2.18, 2.21, 1.85, 2.12]
19
16
35
18.5
22.21
40.7
5.2
0.369
Markedly_Increased
13.8
Proliferative
0
0
1
0
Transabdominal
1
1
0
0
null
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
High
0
0
0
0
1
Metformin
null
0
0
0
1,500
1.08
1
0
0
0
0
0
1
0
0.787
36
0
0
5.9
0
0
40.1
0.647
45
0
4.1
0
1
1
0
0
4.2
0
0
5.1
67.5
12.7
37
43.9
101.9
4.73
69
4
1
0
0
1
1
8
3
25,211
38,772
35,000
3,350
PCOS-0000026
25
Other
172.8
125
41.9
Private
Urban
C
1
0
1
Regular
25.3
13
1
24
1
0
0
22.7
0.1
6.99
7.22
0.97
0.8
37.3
59
10.9
63.8
25
66.7
290.9
239.7
108.5
44.1
8.84
183.9
13.5
1.077
0.787
14.6
10.4
[6.4, 4.99, 7.56, 8.1, 6.17, 6.34, 7.8, 5.92, 5.82, 8.79, 8.32, 7.89, 8.38, 4.03, 9.02]
[65.33, 67.81, 65.31, 63.96, 62.66, 65.23, 62.52, 67.23, 57.42, 61.6, 71.94, 61.26, 62.81, 60.23, 65.11]
[8.7, 8.69, 8.77, 8.34, 8.52, 8.41, 8.33, 8.03, 8.53, 7.97, 7.71, 7.35, 7.38, 7.57, 7.5]
1
0
1
0
0
118.9
29.5
8.65
64
0.28
143.7
124.3
5.4
Prediabetes
1
0
10.65
49.2
381
2.84
2.69
99.5
1.05
178.5
108.9
52.5
85.7
126
118.9
141.8
5.22
3.16
0.5
131
78
1
3
0
0
[8.34, 8.73, 8.45, 8.83, 8.71, 8.73, 8.46, 8.5, 8.83, 9.0, 8.75, 8.47, 8.72, 9.13, 8.67]
24
15
39
15.53
17.51
33.04
9.2
0.382
Increased
12
Secretory
0
0
0
0
Transvaginal
1
1
1
7.4
Letrozole
7.5
60.6
27.4
0
0
2
18
0
0
0
0
0
0
0
0.644
4
22.4
0
0
1
0
0
Critical
0
0
5.5
0
1
Letrozole
null
0
0
0
0
0
0
0
0
0
0
0
1
0
0.699
38
1
0
4.3
0
0
37.1
0.69
37
1
7.3
0
0
1
1
0
3.77
0
0
14.4
25
13
85.7
46.7
95.3
8.99
70
7
1
0
0
1
1
5
5
66,253
61,864
29,962
4,562
PCOS-0000027
23.3
Hispanic
161.2
99.8
38.4
Private
Rural
A
1
1
1
Amenorrhea
92.1
4
1
14.5
1
1
0
17.9
2.5
19.88
1.97
8
2.09
91.4
42
1.96
102.9
25
65.7
308.5
140.6
80.2
32.4
9.39
92.8
16.7
1.558
1.54
6.1
35.3
[19.49, 18.06, 21.29, 18.08, 19.61, 19.82, 20.95, 18.94, 18.85, 20.03, 21.39, 23.31, 17.62, 20.35, 18.25]
[106.99, 99.16, 100.21, 100.55, 102.61, 104.2, 104.84, 102.89, 97.59, 105.82, 102.7, 107.56, 100.08, 96.5, 102.77]
[9.65, 9.3, 9.11, 8.86, 9.26, 8.58, 8.52, 8.66, 8.06, 8.56, 8.31, 8.25, 8.06, 7.8, 7.5]
1
1
1
0
0
97.9
13.8
3.33
119.4
0.28
146.7
275.4
5.3
NGT
1
1
7.97
33.3
391
1.95
3.96
86.1
0.988
197
99.9
55.2
209.7
141.8
112.9
42.8
6.14
7.37
5.66
154
75
0
2
0
0
[3.33, 2.91, 3.34, 3.27, 3.54, 3.45, 3.26, 3.5, 3.52, 3.23, 3.28, 2.93, 3.16, 3.23, 3.39]
14
16
30
12.14
16.33
28.47
9.3
0.44
Increased
4.4
Proliferative
0
0
0
0
Transvaginal
1
1
1
2
Letrozole
7.5
68.8
26.7
0
0
5
16.8
4
25
70.2
54.7
52.9
52.9
1
0.43
4
24.2
0
1
0
0
0
Critical
0
0
5.3
1
1
Spironolactone
null
0
0
0
0
0
0
25
29.5
0
0
0
1
0
0.646
3
0
1
12
0
0
28.9
0.655
26
1
4.7
0
0
0
0
0
4.12
1
0
20.3
25.5
11.8
53.6
37.9
98.8
8.22
65
2
0
1
1
0
0
8
5
67,541
92,450
24,059
1,083
PCOS-0000028
25.7
Other
162.4
98.2
37.2
Medicaid
Rural
C
1
0
1
Regular
27.1
13
1
15.7
1
0
0
25.7
3.7
10.85
6.22
1.75
1.1
68.2
123
14.01
79.2
25
70.7
252.5
248.4
206.7
31.9
8.16
87.2
2
4.502
1.58
5
39.3
[7.33, 11.52, 12.58, 11.4, 11.73, 10.24, 8.06, 11.89, 13.48, 12.55, 7.87, 8.58, 9.59, 8.47, 10.92]
[80.8, 73.51, 82.34, 81.63, 77.04, 78.54, 71.43, 77.9, 79.26, 79.91, 80.75, 80.21, 78.17, 80.37, 83.24]
[8.14, 8.1, 7.88, 7.67, 7.78, 7.45, 7.51, 7.32, 7.14, 7.01, 6.85, 6.51, 6.79, 6.64, 6.65]
1
0
1
0
1
92.2
35.8
8.14
95.4
0.28
107.2
119.9
4.7
NGT
1
0
15.01
43.3
261
3.61
3.07
92.7
0.84
246
135.7
69.1
205.9
176.9
90.3
39.8
3.4
8.26
5.19
127
71
0
2
0
0
[8.23, 8.18, 7.98, 8.32, 7.52, 8.22, 8.66, 7.84, 8.1, 8.14, 8.05, 8.35, 8.24, 8.17, 8.3]
18
30
48
15.9
16.03
31.94
3
0.393
Markedly_Increased
5
Secretory
0
0
0
0
Transvaginal
1
1
1
0.7
Letrozole
5
68.1
33.2
0
0
4
17.3
1
33
78.9
40.4
41.4
39.3
1
0.859
1
35.6
0
0
0
0
0
Critical
0
0
24.1
1
1
OCP
Dienogest
75
44
206
0
0
0
0
0
0
0
0
0
1
0.745
40
0
0
6.2
0
0
30.9
0.687
83
1
7.1
0
0
0
0
0
3.21
1
0
20.3
80.5
13
51.3
52.5
81.5
4.69
83
6
1
0
1
1
1
3
8
52,549
112,634
22,934
2,453
PCOS-0000029
31.1
White
161.6
67.9
26
Private
Urban
B
1
1
0
Amenorrhea
70.1
5.2
1
12.8
0
1
0
24
1.6
4.11
7.35
0.56
1.72
123
113.7
3.37
63.9
25
88.5
135.9
185.1
66
29.9
4
169.1
15.4
3.411
1.362
7.3
17.9
[5.28, 4.07, 5.81, 6.08, 5.91, 5.91, 2.55, 4.83, 3.2, 2.0, 3.68, 6.09, 4.8, 7.13, 4.37]
[73.72, 64.64, 64.02, 58.81, 68.37, 61.92, 61.34, 69.05, 68.56, 68.46, 62.48, 63.72, 63.69, 67.06, 70.14]
[4.07, 4.27, 3.94, 3.59, 3.69, 3.74, 3.68, 3.4, 3.04, 2.88, 2.91, 3.01, 2.65, 2.53, 2.33]
1
0
1
0
0
88.1
12.7
2.76
124.1
0.28
147.8
115.6
5
NGT
1
0
14.87
44.3
562
1.66
3.19
81.6
0.805
207.9
124.1
52.6
155.7
155.3
99
52.6
5.06
12.13
1.09
100
66
0
1
1
0
[2.88, 2.8, 2.87, 2.62, 2.71, 2.76, 2.45, 2.53, 2.54, 2.92, 2.81, 2.88, 2.39, 2.47, 2.89]
2
11
13
3.35
8.69
12.04
12.3
0.312
Normal
18
Hyperplastic
0
0
1
0
Transvaginal
0
1
1
1.8
Letrozole
7.5
71.9
25.5
0
0
6
21.4
5
16
85
64.8
40.4
38
1
0.591
2
30.9
0
0
1
1
0
Low
0
0
20
1
1
OCP
Dienogest
24
46.8
180.2
0
0
0
0
0
0
0
0
0
1
0.86
74
0
0
5.6
0
0
41
0.514
37
0
4.4
0
0
0
1
0
3.33
1
1
8.3
55.5
11
51.8
30.6
88.3
3.75
74
5
0
1
0
0
1
1
5
94,226
89,298
21,821
1,566
PCOS-0000030
22.3
South_Asian
153.6
99.9
42.4
Private
Suburban
D
0
1
1
Amenorrhea
67.4
5.4
0
2.5
0
0
1
22.3
0.6
8.01
9.48
0.85
2.04
97
72.5
3.66
49
25
74.1
117.1
66.9
68.3
29
5.2
132.1
14.1
3.063
0.959
9.5
12
[8.45, 8.13, 4.13, 11.1, 6.67, 11.09, 5.84, 6.8, 4.71, 8.56, 6.36, 6.41, 5.96, 9.18, 9.08]
[56.23, 46.24, 49.86, 43.83, 47.64, 46.91, 50.84, 53.05, 52.95, 45.61, 52.98, 48.81, 47.69, 46.15, 46.75]
[5.55, 5.14, 4.99, 4.79, 5.21, 4.86, 4.33, 4.3, 4.2, 4.15, 3.86, 3.97, 4.05, 3.38, 3.29]
0
0
1
0
0
95
19.3
4.54
162.3
0.28
154.1
252.8
5.1
NGT
1
1
3
48.3
383
3.41
3.57
99.7
1.021
229.5
153.1
30.7
228.7
198.9
100.6
25.6
4.06
9.45
7.51
134
102
1
4
1
0
[4.5, 4.48, 4.45, 4.17, 4.84, 4.46, 4.43, 4.35, 4.54, 4.94, 5.0, 4.25, 4.51, 4.38, 4.78]
17
14
31
14.78
13.13
27.91
12.8
0.447
Increased
3
Proliferative
0
0
0
0
Transabdominal
1
1
0
0
null
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
High
0
0
0
0
1
Inositol
null
0
0
0
0
0
0
0
0
0
0
0
1
0
0.83
4
1
0
6.9
0
0
39.5
0.665
0
0
5.3
0
0
0
0
0
3.43
0
1
25.9
22.6
12
60.7
47.6
93.8
7.53
73
3
1
0
0
0
0
8
6
40,587
72,190
21,686
1,811
PCOS-0000031
34.1
White
161.8
105.4
40.3
Medicaid
Suburban
B
1
1
0
Oligomenorrhea
35
10.4
1
18.2
0
0
0
25.8
1.1
23.07
5.98
3.86
1.74
39.9
45.6
0.36
77.3
25
78.3
330.6
185.7
91
39.3
0.5
90.7
14.9
4.5
1.307
22.8
27
[23.63, 20.03, 23.87, 27.72, 22.88, 22.89, 24.18, 25.54, 24.53, 19.84, 23.91, 26.93, 24.0, 21.34, 23.49]
[72.15, 82.2, 73.45, 77.57, 73.84, 75.09, 83.22, 77.69, 75.04, 72.69, 69.79, 72.27, 77.72, 81.19, 75.03]
[0.81, 0.5, 0.5, 0.5, 0.5, 0.5, 0.5, 0.5, 0.5, 0.5, 0.5, 0.5, 0.5, 0.5, 0.5]
1
1
0
0
0
122.9
21
6.37
89.1
0.28
108.5
244.7
5.5
Prediabetes
1
0
9.61
34.1
372
4.3
3.48
94.5
0.89
232.9
134.3
60.8
189.4
172.2
94.4
10.5
1.24
6.07
1.34
145
82
1
4
0
1
[6.49, 6.2, 6.17, 6.6, 6.44, 6.32, 6.49, 6.37, 6.44, 6.2, 6.78, 6.25, 6.68, 6.33, 6.53]
10
11
21
5.32
9.15
14.47
20.5
0.247
Normal
9.1
Proliferative
0
0
0
1
Transvaginal
1
1
1
0.1
Clomiphene
0
0
0
42.1
19.7
2
8
0
0
0
0
0
0
0
0.585
0
25.5
0
1
0
0
0
Low
0
0
3
1
1
Metformin
null
0
0
0
1,000
0.72
0
0
0
0
0
0
0
0
0.809
56
1
0
8.8
0
0
40.3
0.718
47
0
6.2
0
0
0
1
0
4.84
1
1
5
39.1
12.7
71.3
52.8
69.6
8.01
73
2
1
1
1
1
1
11
7
62,428
99,201
31,196
1,862
End of preview. Expand in Data Studio

HC-END-008 — PCOS Synthetic Dataset (Sample)

XpertSystems.ai · Synthetic Data Factory · Endocrinology Vertical

A comprehensive synthetic cohort of Polycystic Ovary Syndrome patients organized around the Rotterdam phenotypes (A/B/C/D) and spanning HPO-axis hormonal profiles (LH/FSH, androgens, AMH), insulin resistance & metabolic syndrome, ovarian morphology (AFC, volume, endometrium), fertility outcomes (letrozole/clomiphene/IUI/IVF with OHSS risk), pharmacological treatment trajectories, and long-term cardiometabolic risk. This repository contains a 500-row, single-seed sample. The full commercial product scales to 20,000+ patients with 15-year follow-up trajectories and CSV / Parquet / JSON / FHIR R4 delivery.


Validation

This sample passes XpertSystems Grade A+ validation (overall 10.000 / 10) with deterministic reproduction across all six canonical seeds [42, 7, 123, 2024, 99, 1].

Validation philosophy: structural identities over distribution-fit tests — including PCOS physiology checks (hyperandrogenic phenotypes carry higher testosterone). This engine also passes its own built-in 9-benchmark suite (Azziz phenotype distribution, PPCOS-II letrozole live-birth, Rotterdam AFC, AMH elevation, HOMA-IR, metabolic syndrome, SART IVF oocytes, depression, LH/FSH).

Calibration anchors

Metric Sample value Target range Source
Phenotype A fraction 34.2% 31–45% Azziz 2016 (Rotterdam A ~33-43%)
LH/FSH ratio mean 2.66 1.5–3.5 PCOS LH hypersecretion
Elevated AMH fraction 77.0% 40–82% PCOS AMH elevation
Mean HOMA-IR 3.97 2.4–4.5 PCOS insulin resistance
Insulin resistance (HOMA≥2.5) 76.0% 65–85% PCOS IR prevalence
Metabolic syndrome 42.4% 30–50% PCOS MetS prevalence
Letrozole live-birth rate 27.1% 24–31% PPCOS-II (Legro 2014 NEJM ~27.5%)
Depression 36.8% 28–42% PCOS depression prevalence
Testosterone separation (HA−nonHA) 30.6 ng/dL ≥15 Hyperandrogenism physiology
AFC in plausible [4,70] 100% ≥1.0 Ovarian morphology bounds
TSH in [0.01,10] 100% ≥1.0 Assay-range integrity
Column count 190 ≥184 Schema completeness (9 modules)

Schema highlights by module (190 columns)

Demographics. Age, race (incl. South/East Asian PCOS-relevant strata), height/weight/BMI, insurance, region.

Phenotype & diagnosis. Rotterdam A/B/C/D, hyperandrogenism / oligo-anovulation / PCO-morphology flags, menstrual pattern & cycle length, Ferriman-Gallwey, hirsutism/acne/alopecia/acanthosis, diagnosis age & delay.

Hormonal profile. LH/FSH & ratio, GnRH pulse frequency, estradiol/estrone/progesterone, total/free testosterone, SHBG, DHEAS, androstenedione, 17-OHP, DHT, AMH, inhibin B, prolactin, TSH/FT4, cortisol/ACTH; annual LH/testosterone/AMH JSON trajectories; elevation flags.

Insulin resistance & metabolic. Fasting glucose/insulin, HOMA-IR/B, QUICKI, OGTT, HbA1c, glycemic category, adipokines (adiponectin/leptin/ghrelin), C-peptide, VAI, waist/WHR, full lipid panel, inflammatory markers, BP, MetS criteria, NAFLD, sleep apnea, HOMA-IR trajectory.

Ovarian morphology. AFC (R/L/total), ovarian volume, dominant follicle, stromal ratio & echogenicity, endometrial thickness/pattern/hyperplasia/cancer, fibroids, hemorrhagic cyst, Rotterdam AFC & volume criteria.

Fertility. Intent, infertility duration, ovulation induction (letrozole/clomiphene/FSH/GnRH), PPCOS-II-calibrated ovulation & live-birth rates, IUI, IVF (oocytes/fertilization/blastocyst/CPR/ LBR), FET, OHSS risk & events, pregnancy losses, GDM/preeclampsia/preterm/NICU, time-to-conception.

Pharmacotherapy. OCP (progestin type, testosterone reduction, SHBG increase), metformin, spironolactone, GLP-1 RA, inositol, laser/electrolysis, adherence, response, switching.

Cardiometabolic & long-term risk. 10yr CVD risk, events, hypertension onset, carotid IMT, coronary calcium, endothelial dysfunction, endometrial/ovarian/breast cancer, depression/anxiety/ eating disorder, PCOSQ quality of life, sexual dysfunction, body-image distress.

Clinical labs & utilization. Vitamin D, ferritin, hemoglobin, LFTs, eGFR, uric acid, heart rate; visit/referral counts, ultrasound/lab counts, fertility & total costs.

Coding. FHIR R4 Patient bundle (full product).


Files

  • hc_end_008_sample.csv — 500-patient sample (190 columns)
  • generate_sample_dataset_hc_end_008.py — reproducible generator + validation harness
  • validation_report.json / validation_report.md — full scorecard
  • sweep_summary.json — 6-seed determinism results

Loading

import pandas as pd, json
df = pd.read_csv("hc_end_008_sample.csv")
print(df[["patient_id","pcos_phenotype_rotterdam","homa_ir",
          "anti_mullerian_hormone_ng_ml","ovulation_induction_type"]].head())
# Annual trajectories are JSON-encoded:
amh_traj = json.loads(df.loc[0, "amh_trajectory_annual_json"])
from datasets import load_dataset
ds = load_dataset("csv", data_files="hc_end_008_sample.csv")

Use cases

  • PCOS phenotype classification (Rotterdam A/B/C/D from hormone + morphology features)
  • Fertility-outcome modeling (ovulation induction & IVF response prediction)
  • Insulin-resistance and metabolic-syndrome risk stratification
  • OHSS-risk prediction tooling
  • Treatment-response and comparative-effectiveness modeling
  • ML training where real PCOS reproductive-endocrine EHR data is PHI-restricted

Honest limitations & disclosed generator behavior

This is a well-calibrated engine (passes its own 9-benchmark suite, correct PCOS physiology). The following are standard caveats and minor specifics:

  1. Independent symptom/flag draws. Many clinical flags (acne, alopecia, acanthosis, comorbidity flags) are drawn independently conditioned on phenotype, so within-patient symptom clustering is weaker than in real cohorts. Phenotype-level prevalences are correct.
  2. Annual trajectories are simplified. The LH/testosterone/AMH/HOMA-IR JSON arrays are 15-point series generated as baseline + small annual noise (AMH with a mild downward drift); they do not model treatment-driven inflections or pregnancy-related excursions.
  3. Fertility outcomes are marginal rates. Letrozole/clomiphene/IVF success fields are trial-calibrated population rates rather than individual-conditioned outcomes tied to that patient's exact AMH/AFC/age jointly.
  4. Some exclusion conditions are overlays. Hyperprolactinemia and hypothyroidism are applied as independent ~10-12% overlays (as PCOS-mimic exclusions) rather than fully separated diagnoses.

General caveat: cross-field correlations beyond those explicitly modeled may be weaker than in real cohorts. Not for clinical decision-making — research/development use only.


Commercial product comparison

Capability This sample Full HC-END-008 product
Patients 500 20,000+ (configurable)
Follow-up Baseline + 15pt JSON trajectories Full 15-year longitudinal panel
Seeds / cohorts 1 Multi-seed, reproducible
Formats CSV CSV + Parquet + JSON + FHIR R4 Bundle
Symptom clustering Independent draws Correlated within-patient symptom model
Fertility outcomes Marginal trial rates Individual-conditioned joint model
License CC-BY-NC-4.0 Commercial
Support & SLA Included

Full product, custom cohorts, or other endocrinology SKUs: pradeep@xpertsystems.ai


Citation

@dataset{xpertsystems_hc_end_008_2026,
  title        = {HC-END-008: PCOS Synthetic Dataset},
  author       = {XpertSystems.ai},
  year         = {2026},
  publisher    = {XpertSystems.ai Synthetic Data Factory},
  url          = {https://xpertsystems.ai},
  note         = {Synthetic; CC-BY-NC-4.0 (sample). Calibrated to: Azziz et al. 2016
                  (PCOS phenotype epidemiology); PPCOS-II / Legro et al. 2014 NEJM
                  (letrozole vs clomiphene for infertility in PCOS); ESHRE/ASRM Rotterdam
                  consensus criteria; SART national IVF outcomes registry; international
                  evidence-based PCOS guideline (Teede et al. 2018/2023).}
}

Synthetic data generated by XpertSystems.ai. Not derived from real patient records. Not for clinical use.

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